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Electrophilic Fluorination of Silyl Dienol Ethers: a General and Selective Access to γ-Fluoro Enals.

Authors :
Li Y
Briand M
Miqueu K
Anselmi E
Magnier E
Dagousset G
Source :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Feb 16; Vol. 30 (10), pp. e202303545. Date of Electronic Publication: 2023 Dec 28.
Publication Year :
2024

Abstract

We describe the direct synthesis of γ-fluoro enals from the corresponding silyl dienol ethers. This simple process operates under mild conditions and is compatible with a wide range of functionalities. The high γ regioselectivity of this protocol was rationalized by means of theoretical calculations.<br /> (© 2023 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.)

Details

Language :
English
ISSN :
1521-3765
Volume :
30
Issue :
10
Database :
MEDLINE
Journal :
Chemistry (Weinheim an der Bergstrasse, Germany)
Publication Type :
Academic Journal
Accession number :
38055212
Full Text :
https://doi.org/10.1002/chem.202303545