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The German version of the tablet-based UCSF Brain Health Assessment is sensitive to early symptoms of neurodegenerative disorders.
- Source :
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Brain and behavior [Brain Behav] 2023 Dec; Vol. 13 (12), pp. e3329. Date of Electronic Publication: 2023 Dec 02. - Publication Year :
- 2023
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Abstract
- Introduction: Cognition often remains unassessed in primary care. To improve early diagnosis of neurocognitive disorder (NCD) in Switzerland, the tablet-based UCSF brain health assessment (BHA) and brain health survey (BHS) were validated.<br />Methods: The German BHA, BHS, and Montreal Cognitive Assessment (MoCA) were administered to 67 patients with mild/major NCD and 50 controls. BHA includes subtests of memory, executive, visuospatial, and language functioning, and informant-based BHS asks about behavior and motor functioning.<br />Results: The complete instrument (BHA + BHS) was most accurate at detecting mild NCD (AUC = 0.95) and NCD without amyloid pathology (AUC = 0.96), followed by the BHA. All measures were accurate (all AUCs > 0.95) at distinguishing major NCD and NCD with amyloid pathology (Alzheimer's disease [AD]) from controls.<br />Discussion: The German BHA and BHS are more sensitive to mild NCD and non-AD presentations than the MoCA and thus have a high potential to identify patients with NCD in primary care earlier than currently used screens.<br /> (© 2023 The Authors. Brain and Behavior published by Wiley Periodicals LLC.)
Details
- Language :
- English
- ISSN :
- 2162-3279
- Volume :
- 13
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Brain and behavior
- Publication Type :
- Academic Journal
- Accession number :
- 38041514
- Full Text :
- https://doi.org/10.1002/brb3.3329