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Visible-Light-Induced Nickel-Catalyzed Cross-Coupling of Aryl Bromides with Nitriles.
- Source :
-
Organic letters [Org Lett] 2023 Dec 15; Vol. 25 (49), pp. 8824-8828. Date of Electronic Publication: 2023 Nov 30. - Publication Year :
- 2023
-
Abstract
- Herein, a visible-light-induced nickel-catalyzed cross-coupling of aryl bromide with nitrile has been reported. By utilization of readily available nitriles as carbonyl precursors, a range of structurally diverse aryl ketones were facilely constructed. The synthetic simplicity, mild reaction conditions, and acidic functional group tolerance would broaden the synthetic utilities of this developed protocol as an expedient alternative to Grignard/organolithium protocols.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 25
- Issue :
- 49
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 38032230
- Full Text :
- https://doi.org/10.1021/acs.orglett.3c03458