Executive Summary: State-of-the-Art Review: Frame Shift-Focusing on Harm Reduction and Shared Decision Making for People Who Use Drugs Hospitalized With Infections.

Competing Interests: Potential conflicts of interest. J. C. A. M. has served on advisory boards and received an honorarium for Shionogi, Entasis Therapeutics, CSL Sequiris, Innoviva Specialty Therapeutics, and AbbVie, and reports grants or contracts from CSL Sequiris and consulting fees from Shionogi. C. T. reports grants or contracts from the Substance Abuse and Mental Health Services Administration (SAMHSA) and MaineHealth; payment or honoraria for lectures, presentations, speaker’s bureaus, manuscript writing, or educational events from States Recovery in Maine; and a role as a Maine Recovery Council member. K. T. reports grants or contracts from SAMHSA and the National Institutes of Health (NIH); unpaid roles on the Maine Medical Center Board of Directors, Association for Multidisiciplinary Education and Research in Substance use and Addiction. Advocacy Committee, Infectious Diseases Society of America (IDSA) Advocacy subcommittee, and the Maine Recovery Council. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.