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Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart.
- Source :
-
The Biochemical journal [Biochem J] 1986 Jul 01; Vol. 237 (1), pp. 285-8. - Publication Year :
- 1986
-
Abstract
- The activity of branched-chain 2-oxo acid dehydrogenase kinase was 3-fold greater in extracts of heart mitochondria than in extracts of liver mitochondria from rats fed on normal diet. Feeding rats on a 0%-casein diet for 10 days increased the activity of branched-chain kinase 4-fold in extracts of liver mitochondria and in branched-chain dehydrogenase complex purified from such extracts; starvation (48 h) was without effect. In extract of heart mitochondria, kinase activity was increased 2-fold by feeding on 0%-casein diet and 1.5-fold by 48 h of starvation.
- Subjects :
- 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Animals
Electrophoresis, Polyacrylamide Gel
Ketone Oxidoreductases metabolism
Male
Multienzyme Complexes metabolism
Phosphorylation
Rats
Rats, Inbred Strains
Mitochondria, Heart enzymology
Mitochondria, Liver enzymology
Protein Deficiency enzymology
Protein Kinases metabolism
Starvation enzymology
Subjects
Details
- Language :
- English
- ISSN :
- 0264-6021
- Volume :
- 237
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Biochemical journal
- Publication Type :
- Academic Journal
- Accession number :
- 3800883
- Full Text :
- https://doi.org/10.1042/bj2370285