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Agranulocytosis related to vancomycin therapy.
- Source :
-
The American journal of medicine [Am J Med] 1986 Dec; Vol. 81 (6), pp. 1059-61. - Publication Year :
- 1986
-
Abstract
- A patient with renal failure due to Goodpasture's syndrome was treated with vancomycin. After he had received 3 g of the drug, his white blood cell count fell to a level of 200/microliter. Bone marrow biopsy disclosed severe myeloid hypoplasia. The patient subsequently recovered fully from this episode of vancomycin-induced agranulocytosis, but he eventually died of other causes. Vancomycin-related leukopenia has been reported, but the severely depressed white blood cell count and myeloid hypoplasia observed in this patient have not previously been described. Vancomycin must be excluded as the cause of leukopenia in any patient who is receiving this drug.
- Subjects :
- Adult
Anti-Glomerular Basement Membrane Disease complications
Anti-Glomerular Basement Membrane Disease therapy
Cellulitis complications
Cellulitis drug therapy
Combined Modality Therapy
Drug Therapy, Combination
Humans
Leukopenia chemically induced
Male
Agranulocytosis chemically induced
Vancomycin adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9343
- Volume :
- 81
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The American journal of medicine
- Publication Type :
- Academic Journal
- Accession number :
- 3799634
- Full Text :
- https://doi.org/10.1016/0002-9343(86)90407-9