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Complete Response to 177 Lu-DOTATATE PRRT in a 9-Year-Old Child With Metastatic Carotid Body Paraganglioma.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2024 Jan 01; Vol. 49 (1), pp. e33-e34. Date of Electronic Publication: 2023 Nov 16. - Publication Year :
- 2024
-
Abstract
- Abstract: We present a case involving a 9-year-old boy diagnosed with metastatic carotid body paraganglioma. The metastases were detected in cervical lymph nodes and lungs using 68 Ga-DOTANOC PET/CT imaging. The patient received peptide receptor radionuclide therapy with 177 Lu-DOTATATE. Following 3 treatment cycles, a significant improvement was observed in the metastatic lesions. After 4 cycles, the patient achieved a complete response, with a cumulative administered activity of 16.65 GBq during the therapy. This case underscores the effectiveness of using 177 Lu-DOTATATE in managing metastatic carotid body paraganglioma, offering promising results in terms of tumor regression and overall therapeutic response.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Male
Child
Humans
Positron Emission Tomography Computed Tomography
Octreotide therapeutic use
Radioisotopes
Carotid Body Tumor diagnostic imaging
Carotid Body Tumor radiotherapy
Neuroendocrine Tumors pathology
Organometallic Compounds therapeutic use
Peripheral Nervous System Neoplasms
Head and Neck Neoplasms
Paraganglioma diagnostic imaging
Paraganglioma radiotherapy
Paraganglioma drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 49
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 37976428
- Full Text :
- https://doi.org/10.1097/RLU.0000000000004929