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Complete Response to 177 Lu-DOTATATE PRRT in a 9-Year-Old Child With Metastatic Carotid Body Paraganglioma.

Authors :
Yadav MP
Raju S
Ballal S
Bal C
Source :
Clinical nuclear medicine [Clin Nucl Med] 2024 Jan 01; Vol. 49 (1), pp. e33-e34. Date of Electronic Publication: 2023 Nov 16.
Publication Year :
2024

Abstract

Abstract: We present a case involving a 9-year-old boy diagnosed with metastatic carotid body paraganglioma. The metastases were detected in cervical lymph nodes and lungs using 68 Ga-DOTANOC PET/CT imaging. The patient received peptide receptor radionuclide therapy with 177 Lu-DOTATATE. Following 3 treatment cycles, a significant improvement was observed in the metastatic lesions. After 4 cycles, the patient achieved a complete response, with a cumulative administered activity of 16.65 GBq during the therapy. This case underscores the effectiveness of using 177 Lu-DOTATATE in managing metastatic carotid body paraganglioma, offering promising results in terms of tumor regression and overall therapeutic response.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)

Details

Language :
English
ISSN :
1536-0229
Volume :
49
Issue :
1
Database :
MEDLINE
Journal :
Clinical nuclear medicine
Publication Type :
Academic Journal
Accession number :
37976428
Full Text :
https://doi.org/10.1097/RLU.0000000000004929