Back to Search Start Over

[Surgical treatment of pheochromocytoma].

Authors :
Shikhmagomedov SS
Rebrova DV
Krasnov LM
Fedorov EA
Chinchuk IK
Chernikov RA
Rusakov VF
Slepstov IV
Zgoda EA
Source :
Problemy endokrinologii [Probl Endokrinol (Mosk)] 2023 Nov 11; Vol. 69 (5), pp. 39-44. Date of Electronic Publication: 2023 Nov 11.
Publication Year :
2023

Abstract

This review article contains a summary of modern aspects of preoperative preparation, surgical treatment, and follow-up of patients with adrenal pheochromocytomas. The main component of preoperative preparation is the use of alpha-blockers. The need to prescribe them to all patients is increasingly disputed, especially for patients without severe hypertension. An increasing number of publications demonstrate positive results of treatment without the use of alpha-blockers, advocating an individual approach and the use of the drug according to certain indications. Minimally invasive endoscopic techniques of adrenalectomy have become widespread in surgical treatment. They are represented by laparoscopic and retroperitonescopic technic, including using their single-port modifications. The earliest possible intersection of the central vein in the past was considered the most important aspect of adrenalectomy for pheochromocytoma, currently, due to the development of surgical techniques and anesthesiological manuals, this has ceased to be a mandatory rule of successful surgery. Despite the significant influence of the intersection of this vessel on intraoperative hemodynamics, surgical tactics with its later intersection have their own justifications and do not lead to a deterioration in treatment results. The standard volume of surgical intervention for pheochromocytomas is total adrenalectomy, however, in the presence of hereditary syndromes, such as multiple endocrine neoplasia type 2 syndrome, neurofibomatosis type 1, von Hippel-Lindau syndrome, it is possible to perform cortical-sparing adrenalectomy.

Details

Language :
Russian
ISSN :
2308-1430
Volume :
69
Issue :
5
Database :
MEDLINE
Journal :
Problemy endokrinologii
Publication Type :
Academic Journal
Accession number :
37968950
Full Text :
https://doi.org/10.14341/probl13283