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Coumarin-derived Hydroxamic Acids as Histone Deacetylase Inhibitors: A Review of Anti-cancer Activities.
- Source :
-
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2024; Vol. 24 (1), pp. 18-29. - Publication Year :
- 2024
-
Abstract
- Since coumarin and hydroxamic acid compounds are well-known in medicinal chemistry, a variety of their derivatives have been highlighted due to their potential uses for plentiful treatments. Different compounds of their derivatives acting through diverse activities, such as anti-tumor, anti-cancer, anti-inflammation, and histone deacetylase inhibition, have been comprehensively investigated by many researchers over the years. This present review provides the latest literature and knowledge on hydroxamic acids derived from coumarin. Overall, some recent advancements in biological activities of hybrid derivatives of hydroxamic acids containing coumarin moieties in medicinal chemistry are discussed.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
- Subjects :
- Humans
Histone Deacetylase Inhibitors pharmacology
Histone Deacetylase Inhibitors chemistry
Hydroxamic Acids pharmacology
Hydroxamic Acids chemistry
Coumarins pharmacology
Coumarins chemistry
Histone Deacetylases metabolism
Structure-Activity Relationship
Neoplasms drug therapy
Antineoplastic Agents pharmacology
Antineoplastic Agents chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1875-5992
- Volume :
- 24
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Anti-cancer agents in medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 37957868
- Full Text :
- https://doi.org/10.2174/0118715206272112231102063919