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Role of Machine Perfusion in Liver Transplantation.
- Source :
-
The Surgical clinics of North America [Surg Clin North Am] 2024 Feb; Vol. 104 (1), pp. 45-65. Date of Electronic Publication: 2023 Aug 19. - Publication Year :
- 2024
-
Abstract
- Given the current severe shortage of available livers for transplantation, there is an urgent need to maximize the utilization of donor organs. One of the strategies to increase the number of available livers for transplantation is to improve organ utilization through the use of elderly, overweight, or organs donated after circulatory death. However, the utilization of these "marginal" organs was associated with an increased risk of early allograft dysfunction, primary nonfunction, ischemic biliary complications, or even re-transplantation. Ischemia-reperfusion injury is a key mechanism in the pathogenesis of these complications.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1558-3171
- Volume :
- 104
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Surgical clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 37953040
- Full Text :
- https://doi.org/10.1016/j.suc.2023.07.001