Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke.

STAIR XII (12th Stroke Treatment Academy Industry Roundtable) included a workshop to discuss the priorities for advancements in neuroimaging in the diagnostic workup of acute ischemic stroke. The workshop brought together representatives from academia, industry, and government. The participants identified 10 critical areas of priority for the advancement of acute stroke imaging. These include enhancing imaging capabilities at primary and comprehensive stroke centers, refining the analysis and characterization of clots, establishing imaging criteria that can predict the response to reperfusion, optimizing the Thrombolysis in Cerebral Infarction scale, predicting first-pass reperfusion outcomes, improving imaging techniques post-reperfusion therapy, detecting early ischemia on noncontrast computed tomography, enhancing cone beam computed tomography, advancing mobile stroke units, and leveraging high-resolution vessel wall imaging to gain deeper insights into pathology. Imaging in acute ischemic stroke treatment has advanced significantly, but important challenges remain that need to be addressed. A combined effort from academic investigators, industry, and regulators is needed to improve imaging technologies and, ultimately, patient outcomes.
Competing Interests: Disclosures Dr Samaniego reports compensation from Rapid Medical for consultant services; compensation from Medtronic for consultant services; compensation from iSchemaView for consultant services; compensation from MicroVention, Inc, for consultant services; and compensation from Cerenovus for consultant services. Dr Boltze reports compensation from Targed Biopharmaceuticals B.V. for consultant services; employment by the University of Warwick; and compensation from Astrocyte Pharmaceuticals for consultant services. Dr Lyden reports compensation from the NIH Clinical Center for other services; compensation from Apex Innovations for consultant services; and employment by the University of Southern California. Dr Hill reports grants from Medtronic; compensation from Brainsgate, Ltd, for consultant services; grants from Boehringer Ingelheim; grants from Medtronic; grants from NoNO, Inc; a patent issued for Systems and Methods for Assisting in Decision-Making and Triaging for Acute Stroke Patients licensed to Circle NVI; grants from Medtronic; grants from the Canadian Institutes of Health Research; grants from MicroVention, Inc; and employment by the University of Calgary. Dr Campbell reports employment by the University of Melbourne. Dr Nguyen reports compensation from Brainomix for consultant services and compensation from Idorsia for other services. Dr Silva reports compensation from Boehringer Ingelheim for consultant services; employment by UNIFESP; compensation from Bayer for consultant services; compensation from iSchemaView for consultant services; employment by Sociedade Beneficente Israelita Brasileira Albert Einstein; and compensation from Pfizer for other services. Dr Sheth reports stock holdings in Verve Therapeutics; compensation from Rhaeos for consultant services; compensation from Sense for data and safety monitoring services; compensation from Astrocyte for consultant services; compensation from Cerevasc for consultant services; grants from Hyperfine; employment by Yale School of Medicine; a patent pending for Stroke wearables licensed to Alva Health; stock holdings in AbbVie; grants from Biogen; compensation from CSL Behring for consultant services; and compensation from ZOLL Medical Corporation for data and safety monitoring services. Dr Fisher reports compensation from Simcere USA for consultant services; employment by Beth Israel Deaconess Medical Center; compensation from Lumosa for consultant services; and employment by Beth Israel Deaconess Medical Center. Dr Hillis reports employment by the Johns Hopkins University School of Medicine; compensation from Elsevier Publishing for other services; compensation from the National Institute on Deafness and Other Communication Disorders for other services; and compensation from the American Heart Association for other services. Dr Carone reports stock options in Brainomix, Ltd, and employment by Brainomix, Ltd. Dr Deljkich reports employment by Imperative Care, Inc. Dr Albers reports compensation from Genentech for consultant services; stock holdings in iSchemaView; and compensation from iSchemaView for consultant services. Dr Heit reports compensation from Medtronic for consultant services; compensation from iSchemaView for consultant services; and compensation from MicroVention, Inc, for consultant services. The other authors report no conflicts.