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Synthesis, crystal structure and in vitro anti-proliferative activity of 2-[(4-acetyl-phen-yl)carbamo-yl]phenyl acetate.

Authors :
Mohamed-Ezzat RA
Kariuki BM
Srour AM
Source :
Acta crystallographica. Section E, Crystallographic communications [Acta Crystallogr E Crystallogr Commun] 2023 Oct 05; Vol. 79 (Pt 11), pp. 999-1002. Date of Electronic Publication: 2023 Oct 05 (Print Publication: 2023).
Publication Year :
2023

Abstract

2-[(4-Acetyl-phen-yl)carbamo-yl]phenyl acetate, C <subscript>17</subscript> H <subscript>15</subscript> NO <subscript>4</subscript> , has been synthesized and structurally characterized. In the structure, N-H⋯O hydrogen-bonding inter-actions form chains of mol-ecules aligned along the [101] direction. The chains are linked by π-π and C-H⋯π inter-actions, forming a three dimensional network. The compound has been screened for in vitro anti-proliferative activity revealing considerable activity.<br /> (© Mohamed-Ezzat et al. 2023.)

Details

Language :
English
ISSN :
2056-9890
Volume :
79
Issue :
Pt 11
Database :
MEDLINE
Journal :
Acta crystallographica. Section E, Crystallographic communications
Publication Type :
Academic Journal
Accession number :
37936857
Full Text :
https://doi.org/10.1107/S2056989023008526