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Elective management of the N0 neck in maxillary sinus squamous cell carcinoma.
- Source :
-
Head & neck [Head Neck] 2024 Jan; Vol. 46 (1), pp. 171-176. Date of Electronic Publication: 2023 Nov 05. - Publication Year :
- 2024
-
Abstract
- Objectives: To demonstrate adequacy of radiation therapy alone to the neck in patients with maxillary sinus squamous cell carcinoma (MS-SCC) without clinical evidence of regional metastasis.<br />Methods: Retrospective review between 2000 and 2018 from a single high-volume tertiary academic head and neck cancer center of all patients with MS-SCC.<br />Results: A total of 55 patients were treated for MS-SCC at our center. A clinically uninvolved neck on presentation was found in 46 patients (83.6%) in the initial dataset. Of the 39 patients with radiologic N0 disease who were treated with primary surgical resection, 15.4% (6 patients) did not undergo any treatment of the neck, 2.6% (1 patient) underwent a neck dissection only, 69.2% (27 patients) received RT only, and 12.8% (5 patients) were treated with both a neck dissection followed by RT. Median follow-up was 26 months (mean 48 months, interquartile range 9-76 months). Five-year overall survival of all patients with N0 necks treated with upfront surgical resection was 46.5% (95% CI, 32.3%-66.9%). No patients with N0 necks had isolated regional recurrence regardless of neck management.<br />Conclusions: Regional recurrence is rare for patients with radiologic N0 MS-SCC. Single-modality elective neck radiation provides excellent regional disease control in these patients.<br /> (© 2023 The Authors. Head & Neck published by Wiley Periodicals LLC.)
- Subjects :
- Humans
Maxillary Sinus pathology
Follow-Up Studies
Neck pathology
Neck Dissection
Squamous Cell Carcinoma of Head and Neck pathology
Retrospective Studies
Neoplasm Staging
Neoplasm Recurrence, Local pathology
Carcinoma, Squamous Cell surgery
Carcinoma, Squamous Cell pathology
Paranasal Sinus Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1097-0347
- Volume :
- 46
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Head & neck
- Publication Type :
- Academic Journal
- Accession number :
- 37927003
- Full Text :
- https://doi.org/10.1002/hed.27512