Back to Search Start Over

Intracellular Zn(II) induced turn-on fluorescence of an L-phenylalanine-derived pseudopeptide.

Authors :
Tamrakar A
Kumar P
Garg N
Luis SV
Pandey MD
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2023 Nov 15; Vol. 21 (44), pp. 8823-8828. Date of Electronic Publication: 2023 Nov 15.
Publication Year :
2023

Abstract

A C <subscript>2</subscript> symmetric L-phenylalanine-derived pseudopeptide has been synthesized for selective and sensitive recognition of Zn(II) ions in aqueous-organic media. The pseudopeptidic probes exhibit intracellular Zn(II) ion-sensing capabilities as demonstrated via live-cell fluorescence studies on RAW264.7 cells. Hence, we present a bioinspired pseudopeptide for potential biological applications involving intracellular Zn(II) ion detection.

Details

Language :
English
ISSN :
1477-0539
Volume :
21
Issue :
44
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
37906437
Full Text :
https://doi.org/10.1039/d3ob01337e