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Optic atrophy in prematurity: pathophysiology and clinical features.

Authors :
Scott DA
Wang MT
Danesh-Meyer HV
Hull S
Source :
Clinical & experimental optometry [Clin Exp Optom] 2024 Apr; Vol. 107 (3), pp. 245-254. Date of Electronic Publication: 2023 Oct 22.
Publication Year :
2024

Abstract

Optic atrophy is an important cause of visual impairment in children, and the aetiological profile has changed over time. Technological advancements led by neuroimaging of the visual pathway and imaging of the optic nerve with optical coherence tomography have accelerated the understanding of this condition. In the new millennium, an increasing prevalence of prematurity as a cause of optic atrophy in children has been highlighted. This new shift has been linked with increasing rates of premature births and improved neonatal survival of preterm infants. The available literature is limited to hospital and registry-based cohorts with modest sample sizes, methodological heterogeneity and selection bias limitations. Larger studies that are better designed are required to better understand the contribution of prematurity to the disease burden. In addition to considering other life-threatening aetiologies, screening for premature birth should be covered as part of a comprehensive history when evaluating a child with paediatric optic atrophy.

Details

Language :
English
ISSN :
1444-0938
Volume :
107
Issue :
3
Database :
MEDLINE
Journal :
Clinical & experimental optometry
Publication Type :
Academic Journal
Accession number :
37867148
Full Text :
https://doi.org/10.1080/08164622.2023.2256734