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Analysis of General Toxicity of Ergoferon.

Authors :
Danchenko EA
Ertuzun IA
Bugaeva LI
Lebedeva SA
Denisova TD
Lavrova EB
Korzhova TM
Tarasov SA
Source :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2023 Sep; Vol. 175 (5), pp. 644-648. Date of Electronic Publication: 2023 Oct 20.
Publication Year :
2023

Abstract

For antibody-based drugs, it is important and relevant to study their toxic effects, which can often become limiting when prescribing this type of therapy. General toxicity of antiviral drug Ergoferon based on technologically processed antibodies was studied on sexually mature animals. Analysis of acute toxicity showed the absence of lethal outcomes when the drug was administered to adult rats at the maximum tolerated doses. In a study of repeated dose toxicity, no adverse effects of the drug were detected.<br /> (© 2023. Springer Science+Business Media, LLC, part of Springer Nature.)

Details

Language :
English
ISSN :
1573-8221
Volume :
175
Issue :
5
Database :
MEDLINE
Journal :
Bulletin of experimental biology and medicine
Publication Type :
Academic Journal
Accession number :
37861908
Full Text :
https://doi.org/10.1007/s10517-023-05918-8