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Celochalcoside, a new quinochalcone C -glycoside from Celosia trigyna .
- Source :
-
Journal of Asian natural products research [J Asian Nat Prod Res] 2024 May; Vol. 26 (5), pp. 644-651. Date of Electronic Publication: 2023 Oct 16. - Publication Year :
- 2024
-
Abstract
- A new quinochalcone C -glycoside featuring a unique quinonoid moiety, named celochalcoside ( 1 ), was isolated from the n -butanol extract of the aerial parts of Celosia trigyna L. The structure was determined by extensive spectroscopic analysis as well as mass spectrometric data. Compound 1 showed moderate cytotoxic activities against breast cancer cell lines (MCF-7), colon cancer cell lines (HT-29) and hepatocellular carcinoma cell lines (HepG2) with IC <subscript>50</subscript> values of 23.16, 37.05 and 18.35 μg/ml, respectively.
- Subjects :
- Humans
Molecular Structure
Hep G2 Cells
MCF-7 Cells
HT29 Cells
Female
Nuclear Magnetic Resonance, Biomolecular
Drug Screening Assays, Antitumor
Glycosides chemistry
Glycosides pharmacology
Glycosides isolation & purification
Antineoplastic Agents, Phytogenic pharmacology
Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic isolation & purification
Celosia chemistry
Chalcones chemistry
Chalcones pharmacology
Chalcones isolation & purification
Drugs, Chinese Herbal chemistry
Drugs, Chinese Herbal pharmacology
Drugs, Chinese Herbal isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1477-2213
- Volume :
- 26
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of Asian natural products research
- Publication Type :
- Academic Journal
- Accession number :
- 37843408
- Full Text :
- https://doi.org/10.1080/10286020.2023.2269528