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Optimal Follow-up of Incidental Pancreatic Cystic Lesions without Worrisome Features: Clinical Outcome after Long-term Follow-up.
- Source :
-
Gut and liver [Gut Liver] 2024 Mar 15; Vol. 18 (2), pp. 328-337. Date of Electronic Publication: 2023 Oct 10. - Publication Year :
- 2024
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Abstract
- Background/aims: : The optimal duration and interval of follow-up for cystic lesions of the pancreas (CLPs) is not well established. This study was performed to investigate the optimal duration and interval of follow-up for CLPs in clinical practice.<br />Methods: : Patients with CLPs without worrisome features or high-risk stigmata underwent follow-up with computed tomography at 6, 12, 18, and 24 months and then every 12 months thereafter. A retrospective analysis of prospectively collected data was performed.<br />Results: : A total of 227 patients with CLPs detected from 2000 to 2008 (mean initial diameter, 1.3±0.6 cm) underwent follow-up for a median of 120 months. Twenty-two patients (9.7%) underwent surgery after a median of 47.5 months. Malignancies developed in four patients (1.8%), one within 5 years and three within 10 years. One hundred and fourteen patients (50.2%) were followed up for more than 10 years. No malignancy developed after 10 years of follow-up. During surveillance, 37 patients (16.3%) experienced progression to surgical indication. In patients with CLPs less than 2 cm in diameter, development of surgical indications did not occur within 24 months of follow-up.<br />Conclusions: : CLPs should be continuously monitored after 5 years because of the persistent potential for malignant transformation of CLPs. An interval of 24 months for initial follow-up might be enough for CLPs with initial size of less than 2 cm in clinical practice.
- Subjects :
- Humans
Follow-Up Studies
Retrospective Studies
Disease Progression
Pancreas diagnostic imaging
Pancreas surgery
Pancreas pathology
Pancreatic Neoplasms diagnostic imaging
Pancreatic Neoplasms surgery
Pancreatic Neoplasms epidemiology
Pancreatic Cyst diagnostic imaging
Pancreatic Cyst surgery
Pancreatic Cyst pathology
Subjects
Details
- Language :
- English
- ISSN :
- 2005-1212
- Volume :
- 18
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Gut and liver
- Publication Type :
- Academic Journal
- Accession number :
- 37840221
- Full Text :
- https://doi.org/10.5009/gnl230017