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Uveitis in Giant Cell Arteritis: A Retrospective Study of Seven Observational Cases and Literature Review.

Authors :
Gil W
Kodjikian L
Andre M
Kaur I
Durel CA
Hot A
Fauter M
Chaigne B
Smets P
Samson M
Seve P
Source :
Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Oct; Vol. 32 (8), pp. 1844-1851. Date of Electronic Publication: 2023 Oct 10.
Publication Year :
2024

Abstract

Purpose: To describe the demographic and clinical characteristics of uveitis in patients with giant cell arteritis (GCA), their treatments, and evolution.<br />Methods: A national retrospective cohort study was performed. The inclusion criteria were as follows: patients with GCA fulfilling the 2022 ACR/EULAR criteria and a diagnostic of uveitis attested by an ophthalmologist.<br />Results: Seven women were included. The median age at diagnosis of uveitis was 71 years (64-84). All uveitis were diagnosed during active GCA (five at initial diagnosis, two at relapse). All uveitis were acute (100%), mostly anterior (86%) and bilateral (71%). Granulomatous features were less common (29%). All uveitis were treated with local and systemic corticosteroids. After a median follow-up of 30 (21-55) months, all patients achieved complete ophthalmic remission, with only one relapse at 2 years. GCA was also in complete remission.<br />Conclusions: Uveitis could reveal GCA, and its presence correlated with disease activity of GCA. The most frequent clinical presentation of uveitis was acute and anterior; using local and systemic corticosteroids, the prognosis was favorable.

Details

Language :
English
ISSN :
1744-5078
Volume :
32
Issue :
8
Database :
MEDLINE
Journal :
Ocular immunology and inflammation
Publication Type :
Academic Journal
Accession number :
37815855
Full Text :
https://doi.org/10.1080/09273948.2023.2264383