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Uveitis in Giant Cell Arteritis: A Retrospective Study of Seven Observational Cases and Literature Review.
- Source :
-
Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Oct; Vol. 32 (8), pp. 1844-1851. Date of Electronic Publication: 2023 Oct 10. - Publication Year :
- 2024
-
Abstract
- Purpose: To describe the demographic and clinical characteristics of uveitis in patients with giant cell arteritis (GCA), their treatments, and evolution.<br />Methods: A national retrospective cohort study was performed. The inclusion criteria were as follows: patients with GCA fulfilling the 2022 ACR/EULAR criteria and a diagnostic of uveitis attested by an ophthalmologist.<br />Results: Seven women were included. The median age at diagnosis of uveitis was 71 years (64-84). All uveitis were diagnosed during active GCA (five at initial diagnosis, two at relapse). All uveitis were acute (100%), mostly anterior (86%) and bilateral (71%). Granulomatous features were less common (29%). All uveitis were treated with local and systemic corticosteroids. After a median follow-up of 30 (21-55) months, all patients achieved complete ophthalmic remission, with only one relapse at 2 years. GCA was also in complete remission.<br />Conclusions: Uveitis could reveal GCA, and its presence correlated with disease activity of GCA. The most frequent clinical presentation of uveitis was acute and anterior; using local and systemic corticosteroids, the prognosis was favorable.
- Subjects :
- Aged
Aged, 80 and over
Female
Humans
Middle Aged
Follow-Up Studies
Retrospective Studies
Visual Acuity physiology
Giant Cell Arteritis diagnosis
Giant Cell Arteritis complications
Giant Cell Arteritis drug therapy
Glucocorticoids therapeutic use
Uveitis diagnosis
Uveitis drug therapy
Uveitis etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1744-5078
- Volume :
- 32
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Ocular immunology and inflammation
- Publication Type :
- Academic Journal
- Accession number :
- 37815855
- Full Text :
- https://doi.org/10.1080/09273948.2023.2264383