Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies.

Authors :: Furie N
Mandelboim M
Zuckerman N
Belkin A
Seluk L
Shafran I
Mass R
Levy L
Chatterji S
Baltaxe E
Peled M
Shulimzon T
Avigdor A
Amit S
Onn A
Marom EM
Rahav G
Segel MJ
Source :: Open forum infectious diseases [Open Forum Infect Dis] 2023 Sep 15; Vol. 10 (10), pp. ofad464. Date of Electronic Publication: 2023 Sep 15 (Print Publication: 2023).
Publication Year :: 2023
Abstract: We report 8 cases of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in patients previously treated with anti-CD20 monoclonal antibodies. Polymerase chain reaction of nasopharyngeal swabs for SARS-CoV-2 was negative in most cases; viral cell cultures confirmed that viable SARS-Co-2 virus was present. Four patients were treated with anti-SARS-CoV-2 hyperimmune globulins with rapid resolution of disease.<br />Competing Interests: Potential conflicts of interest. All authors: No reported conflicts of interest.<br /> (© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)

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