Multifocal colonic amebomas with delayed bleeding (with video).

Competing Interests: Disclosure All authors disclosed no financial relationships. Commentary Amebiasis is rarely encountered in the United States, and when it is, it is usually seen in individuals who have migrated from endemic areas. Travelers who spend less than a month in an endemic area rarely acquire intestinal amebiasis. Although amebic dysentery can occur, presenting with diarrhea and bloody stools, most (approximately 90%!) Entamoeba infections are asymptomatic. The current case occurred in a patient from an endemic area, but with an important list of comorbid conditions, including renal failure managed with hemodialysis, as well as diabetes. Notably in this case, the patient did not have any GI symptoms, and it was an abnormal positron emission tomography scan that led to the diagnosis of amebic colitis with multiple masslike lesions. It is known that kidney failure as well as diabetes can negatively affect general immunity, increasing susceptibility to infection. It is likely that this patient’s comorbidities contributed to the unusual clinical presentation of this parasitic infection of the colon. David Diehl, MD, GIE Senior Associate Editor Amy Tyberg, MD, FASGE, FACG, Associate Editor for Focal Points