Back to Search
Start Over
[A Case of Testicular Cancer with Solitary Iliac Bone Metastasis].
- Source :
-
Hinyokika kiyo. Acta urologica Japonica [Hinyokika Kiyo] 2023 Sep; Vol. 69 (9), pp. 259-264. - Publication Year :
- 2023
-
Abstract
- A 23-year-old male was aware of pain around his left hip joint and visited a nearby orthopedic clinic. Swelling of the right testis was pointed out, and a testicular tumor was suspected. He was referred to the urology department of a local hospital. Blood analysis showed an increase of α-fetoprotein (AFP) (3,620 ng/ml). Computed tomographic (CT) -scan revealed a left iliac bone metastasis and morbid fracture. Right radical inguinal orchiectomy was performed. The pathological examination revealed mixed germ cell tumor (embryonic carcinoma and immature teratoma: 70%, seminoma: 30%). The diagnosis was non-seminomatous germ cell tumor, stage IIIc, and poor risk on the International Germ Cell Consensus Classification. After one cycle of a bleomycin, etoposide and cisplatinum (BEP) regimen, he was referred to our hospital. After a total of 4 cycles of BEP, AFP was normalized. Denosumab was also administered monthly. The CT-scan showed a reduction of bone metastasis and recovery of ossification. Bone biopsy did not show viable tumor cells. Because extirpation of the remaining mass would require resection of the left part of the pelvic bone with significant functional loss of the left limb, we performed close follow-up after an additional 2 courses of the etoposide and cisplatin regimen. The patient is currently alive without recurrence at 45 months after the last systemic chemotherapy.
- Subjects :
- Male
Humans
Young Adult
Adult
Etoposide therapeutic use
alpha-Fetoproteins analysis
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Cisplatin
Bleomycin therapeutic use
Orchiectomy
Testicular Neoplasms diagnostic imaging
Testicular Neoplasms drug therapy
Testicular Neoplasms pathology
Neoplasms, Germ Cell and Embryonal drug therapy
Neoplasms, Germ Cell and Embryonal surgery
Bone Neoplasms diagnostic imaging
Bone Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0018-1994
- Volume :
- 69
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Hinyokika kiyo. Acta urologica Japonica
- Publication Type :
- Academic Journal
- Accession number :
- 37794677
- Full Text :
- https://doi.org/10.14989/ActaUrolJap_69_9_259