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Circadian activity rhythms in rats with midbrain raphe lesions.
- Source :
-
Brain research [Brain Res] 1986 Oct 08; Vol. 384 (2), pp. 240-9. - Publication Year :
- 1986
-
Abstract
- The dorsal and median mesencephalic raphe nuclei provide a robust projection to the hypothalamic suprachiasmatic nucleus, the site of a putative neuronal circadian pacemaker. Although it has been suggested that the raphe may play a role in the circadian timing system, this role has not yet been specified. In the present report, we examined the circadian activity patterns of rats with large mid-brain lesions aimed at the median and dorsal raphe nuclei under conditions of light-dark entrainment, and while free-running in constant light and constant darkness. The results indicate that midbrain raphe lesions may interfere with the expression of free-running circadian activity rhythms.
Details
- Language :
- English
- ISSN :
- 0006-8993
- Volume :
- 384
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Brain research
- Publication Type :
- Academic Journal
- Accession number :
- 3779378
- Full Text :
- https://doi.org/10.1016/0006-8993(86)91160-1