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Recording uterine motility in the nonanesthetized bitch.

Authors :
Wheaton LG
Rodriguez-Martinez H
Weston PG
Ko CH
Gustafsson BK
Source :
American journal of veterinary research [Am J Vet Res] 1986 Oct; Vol. 47 (10), pp. 2205-7.
Publication Year :
1986

Abstract

Spontaneous and drug-induced uterine motility (UM) was recorded in 5 nonanesthetized bitches for 2 to 4 days. Catheter-tip pressure transducers were surgically implanted in 1 uterine horn, tunneled subcutaneously to exit from the skin over the dorsal lumbar area, and protected by a bandage. On the day after implantation, spontaneous UM was recorded in the awake bitch. Effects of IV prostaglandin (PG) F2 alpha (5 micrograms/kg of body weight) and oxytocin (0.05 USP U/kg) and IM PGF2 alpha (25 micrograms/kg) were measured. Estradiol (1 to 25 micrograms/kg) was administered and the study was repeated 24 hours later. In awake bitches, spontaneous UM was 190% greater than UM in anesthetized bitches. Uterine motility was increased by more than 100% after IV PGF2 alpha or oxytocin and by 52% after IM PGF2 alpha. Estradiol abolished spontaneous UM, but did not affect drug-induced responses. Seemingly, spontaneous and drug-induced UM can be documented in the nonanesthetized bitch.

Details

Language :
English
ISSN :
0002-9645
Volume :
47
Issue :
10
Database :
MEDLINE
Journal :
American journal of veterinary research
Publication Type :
Academic Journal
Accession number :
3777647