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SARS-CoV-2 Infection, Vaccination and Risk of Death in People with An Oncological Disease in Northeast Italy.
- Source :
-
Journal of personalized medicine [J Pers Med] 2023 Aug 29; Vol. 13 (9). Date of Electronic Publication: 2023 Aug 29. - Publication Year :
- 2023
-
Abstract
- People with a history of cancer have a higher risk of death when infected with SARS-CoV-2. COVID-19 vaccines in cancer patients proved safe and effective, even if efficacy may be lower than in the general population. In this population-based study, we compare the risk of dying of cancer patients diagnosed with COVID-19 in 2021, vaccinated or non-vaccinated against SARS-CoV-2 and residing in Friuli Venezia Giulia or in the province of Reggio Emilia. An amount of 800 deaths occurred among 6583 patients; the risk of death was more than three times higher among unvaccinated compared to vaccinated ones [HR 3.4; 95% CI 2.9-4.1]. The excess risk of death was stronger in those aged 70-79 years [HR 4.6; 95% CI 3.2-6.8], in patients with diagnosis made <1 year [HR 8.5; 95% CI 7.3-10.5] and in all cancer sites, including hematological malignancies. The study results indicate that vaccination against SARS-CoV-2 infection is a necessary tool to be included in the complex of oncological therapies aimed at reducing the risk of death.<br />Competing Interests: The authors declare that the research was conducted without any commercial or financial relationships construed as a potential conflict of interest.
Details
- Language :
- English
- ISSN :
- 2075-4426
- Volume :
- 13
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Journal of personalized medicine
- Publication Type :
- Academic Journal
- Accession number :
- 37763101
- Full Text :
- https://doi.org/10.3390/jpm13091333