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Incidental DCIS within a fibroadenoma.

Authors :
Chen A
Kanakaratne S
Britten-Jones P
Bingham J
Source :
BMJ case reports [BMJ Case Rep] 2023 Sep 26; Vol. 16 (9). Date of Electronic Publication: 2023 Sep 26.
Publication Year :
2023

Abstract

A female in her early 20s was referred to the breast-endocrine surgeons with a self-detected tender left breast lump on the background of a family history of breast cancer. A physical examination revealed a rubbery and mobile mass in the left upper breast. Ultrasound demonstrated a solid hypoechoic mass with a likely differential diagnosis of fibroadenoma, with a subsequent core needle biopsy (CNB) confirming a fibroadenoma. Given the size and tenderness of the lump, an excisional biopsy was performed. Histology revealed a fibroadenoma with components of low-grade ductal carcinoma in situ, contained within the fibroadenoma and excised with clear margins.Following surgical excision, a multidisciplinary review determined that no further local therapy was required and recommended a genetics referral. This case was interesting as it raised important questions, including what the best surveillance strategies are for female patients with breast cancer within fibroadenoma and determining the risk and probability of missing epithelial atypia via CNB.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.)

Details

Language :
English
ISSN :
1757-790X
Volume :
16
Issue :
9
Database :
MEDLINE
Journal :
BMJ case reports
Publication Type :
Academic Journal
Accession number :
37751969
Full Text :
https://doi.org/10.1136/bcr-2023-254609