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Contact allergy to rubber accelerators in consecutively patch tested Danish eczema patients: A retrospective observational study from 1990 to 2019.
- Source :
-
Contact dermatitis [Contact Dermatitis] 2024 Feb; Vol. 90 (2), pp. 116-125. Date of Electronic Publication: 2023 Sep 21. - Publication Year :
- 2024
-
Abstract
- Background: Rubber accelerators are used in the production of rubber gloves and may cause contact allergy.<br />Objectives: To estimate long-term trend and prevalence of contact allergy to rubber accelerators for a 30-year period in Denmark, high-risk occupations, and exposures.<br />Methods: Data from all patients with contact dermatitis consecutively patch tested at the department of Skin and Allergy Gentofte hospital with the rubber accelerators from the European baseline series (EBS) from 1990 to 2019, were analysed. Further, patients under suspicion of rubber accelerator contact allergy were additionally patch-tested with rubber accelerators from the specialised rubber series from 2005 to 2019 and these were additional extracted.<br />Results: The overall prevalence of contact allergy to one or more of the rubber accelerators from the EBS series was 2.7% with a significant decline in the first 12-years, followed by a stable frequency in the past 18-years. Associations with occupational contact dermatitis, hand dermatitis, and leg/foot dermatitis were found. Wet-work occupations were most often affected and gloves the most frequent exposure.<br />Conclusions: Contact allergy to one or more of the rubber accelerators from the EBS is frequent and has been unchanged for several decades, which calls for prevention.<br /> (© 2023 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.)
- Subjects :
- Humans
Rubber adverse effects
Patch Tests adverse effects
Denmark epidemiology
Dermatitis, Allergic Contact diagnosis
Dermatitis, Allergic Contact epidemiology
Dermatitis, Allergic Contact etiology
Dermatitis, Occupational etiology
Dermatitis, Occupational complications
Latex Hypersensitivity epidemiology
Eczema epidemiology
Eczema complications
Subjects
Details
- Language :
- English
- ISSN :
- 1600-0536
- Volume :
- 90
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Contact dermatitis
- Publication Type :
- Academic Journal
- Accession number :
- 37735996
- Full Text :
- https://doi.org/10.1111/cod.14421