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Association of Yersinia Infection With Kawasaki Disease: A Prospective Multicenter Cohort Study.
- Source :
-
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2023 Dec 01; Vol. 42 (12), pp. 1041-1044. Date of Electronic Publication: 2023 Sep 07. - Publication Year :
- 2023
-
Abstract
- Background: Yersinia infection is known to present with Kawasaki disease (KD)-like symptoms although differentiating the 2 has been a challenge. The present study aimed to describe the clinical characteristics and prevalence of Yersinia infection presenting with KD-like symptoms.<br />Methods: The present, prospective, multicenter study enrolled patients who received a diagnosis of KD between January 2021 and January 2022 at 2 hospitals in Tokyo. Stool samples were collected within 3 days of the start of KD treatment, and cultures were performed for Yersinia . Clinical history and symptoms suggestive of Yersinia infection were also evaluated.<br />Results: During the study period, 141 KD patients were screened and 117 patients with evaluable stool samples were registered. Only 1 patient was positive for Yersinia pseudotuberculosis , which was detected from both stool and blood cultures. The patient was refractory to KD treatment but improved after initiation of appropriate antibiotic therapy.<br />Conclusions: Routine screening for Yersinia is not appropriate for patients with KD and should be limited to certain patients in high-risk areas and those who are refractory to the standard KD treatment.<br />Competing Interests: The authors have no funding or conflicts of interest to disclose.<br /> (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Humans
Prospective Studies
Mucocutaneous Lymph Node Syndrome complications
Mucocutaneous Lymph Node Syndrome diagnosis
Mucocutaneous Lymph Node Syndrome epidemiology
Yersinia pseudotuberculosis Infections complications
Yersinia pseudotuberculosis Infections diagnosis
Yersinia pseudotuberculosis Infections epidemiology
Yersinia Infections complications
Yersinia Infections epidemiology
Yersinia pseudotuberculosis
Subjects
Details
- Language :
- English
- ISSN :
- 1532-0987
- Volume :
- 42
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Pediatric infectious disease journal
- Publication Type :
- Academic Journal
- Accession number :
- 37725804
- Full Text :
- https://doi.org/10.1097/INF.0000000000004084