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Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2).

Authors :
Towns C
Richer M
Jasaityte S
Stafford EJ
Joubert J
Antar T
Martinez-Carrasco A
Makarious MB
Casey B
Vitale D
Levine K
Leonard H
Pantazis CB
Screven LA
Hernandez DG
Wegel CE
Solle J
Nalls MA
Blauwendraat C
Singleton AB
Tan MMX
Iwaki H
Morris HR
Source :
NPJ Parkinson's disease [NPJ Parkinsons Dis] 2023 Sep 12; Vol. 9 (1), pp. 131. Date of Electronic Publication: 2023 Sep 12.
Publication Year :
2023

Abstract

The Global Parkinson's Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia.<br /> (© 2023. Springer Nature Limited.)

Details

Language :
English
ISSN :
2373-8057
Volume :
9
Issue :
1
Database :
MEDLINE
Journal :
NPJ Parkinson's disease
Publication Type :
Academic Journal
Accession number :
37699923
Full Text :
https://doi.org/10.1038/s41531-023-00533-w