Clinical Relevance of RSV and SARS-CoV-2 Coinfections in Infants and Young Children.

We analyzed the frequency, clinical impact and severity of respiratory syncytial virus (RSV) and SARS-CoV-2 coinfections in a single pediatric center between March 2020 and January 2023. Compared to single RSV infections, RSV/SARS-CoV-2 coinfections were uncommon (2.1%), occurred more frequently during circulation of omicron, and were associated with increased disease severity as defined by longer hospitalization and increased need for high-flow nasal cannula.
Competing Interests: R.R-.F. has received fees for lectures from Abbvie, Astra Zeneca, Pfizer and Sanofi, fees for participation in Advisory Boards from Sanofi, Astra Zeneca and Merck, and research grants from FIS (Fondo de Investigaciones Sanitarias). O.R. has received research grants to institution from Janssen, Merck, NIH and the Bill & Melinda Gates foundation; and fees for participation in Advisory Boards from Sanofi-Pasteur, Merck, Lilly, Adagios and Pfizer and for lectures from Pfizer, Sanofi-Pasteur and Astra-Zeneca. A.M. has received fees for participation in Advisory Boards from Janssen, Merck, Pfizer and Sanofi-Pasteur, grants to institution from Merck and Janssen, and fees for lectures from Sanofi-Pasteur and Astra-Zeneca. The other authors have no conflicts of interest to disclose.
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