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Exocrine pancreatic insufficiency following bariatric surgery: unveiling alternative aetiology-case report and short review.

Authors :
Milad C
Nunez-Pizarro JL
Ibarzábal A
Claro M
Leyes P
Vaquero E
Moizé V
Jiménez A
Molero X
de Hollanda A
Source :
European journal of clinical nutrition [Eur J Clin Nutr] 2023 Dec; Vol. 77 (12), pp. 1173-1175. Date of Electronic Publication: 2023 Sep 04.
Publication Year :
2023

Abstract

Bariatric surgery (BS) is currently the most effective treatment for severe obesity, requiring ongoing multidisciplinary follow-up to ensure proper progress and nutrition post-procedure. Despite its favourable safety profile, it is not exempt from complications, one of which being exocrine pancreatic insufficiency (EPI). The underlying pathophysiological mechanisms of EPI after BS are multifactorial, including poorly synchronized pancreatic enzyme secretion with the passage of nutrients (pancreaticocibal or postcibal asynchrony), insufficient pancreatic stimulation and bacterial overgrowth. We conducted a short literature review of the topic through a case of a patient who underwent BS in our centre and subsequently developed EPI and severe malnutrition. EPI initially was attributed to the surgery, but after a comprehensive evaluation, an unexpected cause was revealed.<br /> (© 2023. The Author(s), under exclusive licence to Springer Nature Limited.)

Details

Language :
English
ISSN :
1476-5640
Volume :
77
Issue :
12
Database :
MEDLINE
Journal :
European journal of clinical nutrition
Publication Type :
Academic Journal
Accession number :
37666959
Full Text :
https://doi.org/10.1038/s41430-023-01338-z