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Ischemic strokes revealing neurosyphilis: Study of six (6) observations at the neurology Department of the University Hospital of Conakry.
- Source :
-
ENeurologicalSci [eNeurologicalSci] 2023 Jun 14; Vol. 32, pp. 100470. Date of Electronic Publication: 2023 Jun 14 (Print Publication: 2023). - Publication Year :
- 2023
-
Abstract
- Introduction: In sub-Saharan Africa (SSA), stroke is a major public health problem and the etiological aspects are poorly studied and documented because of under-medicalization; the syphilitic etiology is rarely mentioned.<br />Patients and Methods: We performed a retrospective study of 472 patients hospitalized for ischemic stroke between 2016 and 2021 in the Neurology Department of the University Hospital of Conakry, confirmed by neuroradiological explorations (brain CT, MRI-Angio) and a biological workup including VDRL-TPHA serological reactions in blood and CSF.<br />Results: Syphilitic etiology was retained for six (6) patients (4 men and 2 women) with a mean age of 43 years (extremes 36 and 49 years). The clinical picture was dominated by carotid syndromes: superficial and deep sylvian syndrome, anterior cerebral artery syndrome and vertebro-basilar syndromes and one case of lacunar syndrome.The diagnosis was based on the positivity of serological reactions (VDRL-TPHA) in blood and cerebrospinal fluid (CSF) and the presence of a predominantly lymphocytic hypercellularity and a hyperproteinorachy in the CSF in the absence of any other etiology.<br />Conclusion: These neurological vascular syndromes consecutive to a cerebral treponematous attack are often the result of a still poorly conducted management of primary and secondary syphilis in our country.<br />Competing Interests: None.<br /> (© 2023 The Authors.)
Details
- Language :
- English
- ISSN :
- 2405-6502
- Volume :
- 32
- Database :
- MEDLINE
- Journal :
- ENeurologicalSci
- Publication Type :
- Academic Journal
- Accession number :
- 37654736
- Full Text :
- https://doi.org/10.1016/j.ensci.2023.100470