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Difficulties on the access to innovative targeted therapies for lung cancer in Spain.

Authors :
Calvo V
Camps C
Carcereny E
Cobo M
Dómine M
García Campelo MR
González Larriba JL
Guirado M
Hernando-Trancho F
Massutí B
Nadal E
Rodríguez-Abreu D
Sánchez A
Sullivan IG
Provencio M
Source :
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2024 Mar; Vol. 26 (3), pp. 597-612. Date of Electronic Publication: 2023 Aug 31.
Publication Year :
2024

Abstract

Purpose: Spanish Lung Cancer Group (SLCG) conducted a review to analyze the barriers to access to innovative targeted therapies for non-small cell lung cancer (NSCLC) in clinical practice in Spain.<br />Methods: Review all relevant content published on websites of European Commission, European Medicines Agency, and Spanish Agency of Medicines and Medical Products regarding the authorization and access to oncology treatments.<br />Results: More than 20 targeted therapies are available to treat different molecular alterations in patients with NSCLC. European Commission has approved treatments for genomic alterations involving the following genes: ALK, RET, ROS1, EGFR, BRAF, NTRK, KRAS, MET. However, the availability of these therapies in Spain is not complete, as innovative treatments are not reimbursed or funded late, with only five of these alterations currently covered by National Health System.<br />Conclusion: SLCG considers imperative to improve the access in Spain to innovative treatments for NSCLC to reduce inequity across European countries.<br /> (© 2023. The Author(s).)

Details

Language :
English
ISSN :
1699-3055
Volume :
26
Issue :
3
Database :
MEDLINE
Journal :
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Publication Type :
Academic Journal
Accession number :
37651020
Full Text :
https://doi.org/10.1007/s12094-023-03303-5