"Click" Chemistry for the Functionalization of Graphene Oxide with Phosphorus Dendrons: Synthesis, Characterization and Preliminary Biological Properties.

Authors :: Alami O
Laurent R
Tassé M
Coppel Y
Bignon J
El Kazzouli S
Majoral JP
El Brahmi N
Caminade AM
Source :: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Nov 24; Vol. 29 (66), pp. e202302198. Date of Electronic Publication: 2023 Oct 16.
Publication Year :: 2023
Abstract: Two families of phosphorhydrazone dendrons having either an azide or an alkyne linked to the core and diverse types of pyridine derivatives as terminal functions have been synthesized and characterized. These dendrons were grafted via click reaction to graphene oxide (GO) functionalized with either alkyne or azide functions, respectively. The resulting modified-GO and GO-dendrons materials have been characterized by Fourier Transform Infrared (FTIR), Raman spectroscopy (RS), and Magic Angle Spinning Nuclear Magnetic Resonance (MAS NMR) analyses. In addition, the free dendrons and the dendrons grafted to GO were tested toward cancerous (HCT116) and non-cancerous (RPE1) cell lines.<br /> (© 2023 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.)

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