Novel breathing pattern analysis: Symmetric Projection Attractor Reconstruction improves identification of impending COPD re-exacerbations - a retrospective cohort analysis.

Respiratory waveforms can be reduced to simple metrics, such as rate, but this may miss information about waveform shape and whole breathing pattern. A novel analysis method quantifying the whole waveform shape identifies AECOPD earlier. https://bit.ly/3M6uIEB.
Competing Interests: Conflict of interest: M. Nandi and P.J. Aston are coinventors of SPAR method – Delay coordinate analysis of periodic data, patent number WO2015121679A1, used in this study. Conflict of interest: N. Hart is involved in an investigator-led/industry-funded trial (unrestricted grant) with Resmed. He receives consulting fees from Philips for a hospital patient monitoring programme. He has received payments and honoraria from Fisher and Paykel (chairing an ERS International Congress 2022 symposium) and Philips (lecturing at an ERS International Congress 2022 symposium). He has received financial support for attending meetings from Fisher and Paykel (ERC 2022). He has patents planned, issued or pending for Myotrace (held by Guy's and Thomas’ Foundation Trust). Conflict of interest: R.F. D'Cruz receives consulting fees from Resmed and AstraZeneca. She receives payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing or educational events from Fisher Paykel and Resmed. She receives support for attending meetings from Fisher Paykel and Resmed. Conflict of interest: M. Serna-Pascual, M. Volovaya, C.J. Jolley, G.F. Rafferty and J. Steier have declared no conflict of interest.
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