Editing a rice CDP-DAG synthase confers broad-spectrum resistance.

Authors :: You X
Ning Y
Wang GL
Source :: Trends in plant science [Trends Plant Sci] 2023 Dec; Vol. 28 (12), pp. 1344-1346. Date of Electronic Publication: 2023 Aug 28.
Publication Year :: 2023
Abstract: Lesion mimic mutations (LMMs) often confer broad-spectrum resistance (BSR) in plants, but with significant yield penalties. Sha et al. recently demonstrated that genome editing of the rice BSR gene RESISTANCE TO BLAST1 (RBL1), encoding a cytidine diphosphate diacylglycerol (CDP-DAG) synthase involved in phospholipid biosynthesis, confers multipathogen resistance without an obvious trade-off in yield.<br />Competing Interests: Declaration of interests The authors declare that they have no conflict of interest.<br /> (Copyright © 2023 Elsevier Ltd. All rights reserved.)