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[An autopsied patient with palatal tremor and fatal bilateral vocal cord abduction paralysis associated with bilateral cerebellar dentate nucleus infarction].

Authors :
Sato T
Saito R
Sainouchi M
Mezaki N
Miura T
Mashima T
Kakita A
Source :
Rinsho shinkeigaku = Clinical neurology [Rinsho Shinkeigaku] 2023 Sep 20; Vol. 63 (9), pp. 572-576. Date of Electronic Publication: 2023 Aug 29.
Publication Year :
2023

Abstract

A 74-year-old male patient developed multiple infarcts of the brainstem and cerebellum, followed 14 months later by palatal tremor and bilateral vocal cord abduction paralysis, resulting in death due to type 2 respiratory failure. Pathologic analysis revealed old infarcts extending from the bilateral cerebellar cortices to the dentate nucleus, being more extensive on the right side, accompanied by Wallerian degeneration involving the left red nucleus, right central tegmentum tract, and inferior cerebellar peduncle, followed by pseudohypertrophy of the bilateral inferior olivary nuclei. These lesions, involving the Guillain-Mollaret triangle, may have been responsible for the palatal tremor. On the other hand, there were no evident causative lesions for the vocal cord abduction, including any in the nucleus ambiguus or posterior cricoarytenoid muscles. In this case it is possible that the dysfunction responsible for the palatal tremor may have affected the pathway from the central tegmentum tract, which is part of the Guillain-Mollaret triangle, to the vagus nerve arising from the nucleus ambiguus, which plays a role in vocal cord abduction, thus affecting the vocal cords and resulting in abduction paralysis.

Details

Language :
Japanese
ISSN :
1882-0654
Volume :
63
Issue :
9
Database :
MEDLINE
Journal :
Rinsho shinkeigaku = Clinical neurology
Publication Type :
Academic Journal
Accession number :
37648478
Full Text :
https://doi.org/10.5692/clinicalneurol.cn-001859