Back to Search
Start Over
Stalled but not forgotten: Bacterial exotoxins inhibit translation to activate NLRP1.
- Source :
-
The Journal of experimental medicine [J Exp Med] 2023 Oct 02; Vol. 220 (10). Date of Electronic Publication: 2023 Aug 29. - Publication Year :
- 2023
-
Abstract
- In this issue of JEM, companion articles from Pinilla et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20230104) and Robinson et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20230105) demonstrate that ribotoxic stress induced by Pseudomonas aeruginosa and Corynebacterium diphtheriae EEF2-targeting exotoxins leads to NLRP1 inflammasome activation, representing a new mechanism of effector-triggered immunity.<br />Competing Interests: Disclosures: The authors declare no competing financial interests.<br /> (© 2023 Tibble et al.)
Details
- Language :
- English
- ISSN :
- 1540-9538
- Volume :
- 220
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- The Journal of experimental medicine
- Publication Type :
- Academic Journal
- Accession number :
- 37642998
- Full Text :
- https://doi.org/10.1084/jem.20231160