Back to Search
Start Over
Human chromosome hot points. V. The effect of four nucleosides on chromosomes in folate-free medium.
- Source :
-
Human genetics [Hum Genet] 1986 Sep; Vol. 74 (1), pp. 101-3. - Publication Year :
- 1986
-
Abstract
- Human lymphocytes from 18 healthy adults were cultured in minimal essential medium without folic acid. The addition of 4 mM cytidine or 1 mM guanosine to cultures 24 h prior to harvest produced a statistically significant increase in hot point 3p14 breaks. An excess of 3 mM adenosine or thymidine had no such effect on the hot point. The mechanism of the effects of nucleosides on hot points was discussed.
Details
- Language :
- English
- ISSN :
- 0340-6717
- Volume :
- 74
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Human genetics
- Publication Type :
- Academic Journal
- Accession number :
- 3759083
- Full Text :
- https://doi.org/10.1007/BF00278795