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Diversity of bla L1-like genes in Stenotrophomonas species: insights from genome analysis of publicly available genome sequences.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2023 Sep 19; Vol. 67 (9), pp. e0067323. Date of Electronic Publication: 2023 Aug 16. - Publication Year :
- 2023
-
Abstract
- L1 metallo-β-lactamases produced by Stenotrophomonas maltophilia exhibit high diversity. Here, we characterized the genomes of Stenotrophomonas species harboring bla <subscript>L1-like</subscript> genes using publicly available genome sequences. Our findings provide evidence that Stenotrophomonas species with bla <subscript>L1-like</subscript> genes constitute a complex comprising many species with high genetic diversity, and similarities between bla <subscript>L1-like</subscript> genes are lower than those of the genome. This suggests that the diversity of bla <subscript>L1-like</subscript> is attributable to species diversity in Stenotrophomonas species harboring bla <subscript>L1-like</subscript> and the rapid evolutionary changes in bla <subscript>L1-like</subscript> genes.<br />Competing Interests: The authors declare no conflict of interest.
Details
- Language :
- English
- ISSN :
- 1098-6596
- Volume :
- 67
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 37584548
- Full Text :
- https://doi.org/10.1128/aac.00673-23