Back to Search
Start Over
Use of non-invasive scales for detecting esophageal varices in paediatric patients with portal vein thrombosis.
- Source :
-
Gastroenterologia y hepatologia [Gastroenterol Hepatol] 2024 May; Vol. 47 (5), pp. 433-438. Date of Electronic Publication: 2023 Aug 09. - Publication Year :
- 2024
-
Abstract
- Introduction: Portal vein thrombosis (PVT) is the most frequent cause of portal hypertension in paediatric population. Baveno VI Consensus considers endoscopic variceal ligation as the second therapeutic option after meso-Rex bypass (surgical shunt).<br />Aim: Analyse the diagnostic profitability of non-invasive scales in order to predict the risk of oesophageal varices (OV) in children with PVT.<br />Material and Methods: Descriptive retrospective study where every upper gastrointestinal endoscopy (UGE) carried on patients <15 years old with non-cirrhotic PVT were included. There were divided according to the presence of OV and sex, cause, age, previous gastrointestinal bleeding or treatments, results of UGE and scales (Clinical Prediction Rule - CPR), Varices Prediction Rule - VPR), King's Variceal Prediction Score - K-VaPS) and Platelet count/Spleen diameter Ratio - PSR). Qualitative variables were expressed as absolute frequency and percentage, and quantitative variables as median and interquartile range. U Mann-Whitney and Hanley-McNeil tests were used for comparisons.<br />Results: Forty-five UGE were analysed. 80% (n=36) presented OV: median of 3 (2-3) and 33.3% (n=12) required endoscopic variceal ligation. Statistical differences were demonstrated between both groups: CPR (142.39 [132.22-166.53] vs. 122.75 [115.24-133.15]; p=0.003), VPR (9.91 [9.36-11.75] vs. 5.6 [3.34-8.39]; p=0.001), K-VaPS (117.86 [99.66-126.58] vs. 99.64 [94.88-10.18]; p=0.019), PSR (2384.62 [1902.22-3201.63] vs. 1252.5 [579.6-2144.42]; p=0.05), with and area under the curve AUROC>75%, without statistical differences between scales.<br />Conclusions: In paediatric patients with non-cirrotic PVT non-invasive scales can be used as a tool to predict the presence of OV and raise the indication of UGE.<br /> (Copyright © 2023 Elsevier España, S.L.U. All rights reserved.)
- Subjects :
- Humans
Retrospective Studies
Male
Female
Child
Child, Preschool
Adolescent
Hypertension, Portal complications
Endoscopy, Gastrointestinal
Platelet Count
Infant
Ligation
Gastrointestinal Hemorrhage etiology
Esophageal and Gastric Varices etiology
Esophageal and Gastric Varices diagnosis
Venous Thrombosis diagnostic imaging
Venous Thrombosis complications
Portal Vein diagnostic imaging
Subjects
Details
- Language :
- English; Spanish; Castilian
- ISSN :
- 0210-5705
- Volume :
- 47
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Gastroenterologia y hepatologia
- Publication Type :
- Academic Journal
- Accession number :
- 37562768
- Full Text :
- https://doi.org/10.1016/j.gastrohep.2023.08.001