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Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection.

Authors :
Hamada T
Katsuta T
Aibara K
Nozu S
Nakamura J
Kondo H
Tachibana S
Inoue K
Nakanishi N
Moritaka T
Source :
Respiratory medicine case reports [Respir Med Case Rep] 2023 Jul 16; Vol. 45, pp. 101890. Date of Electronic Publication: 2023 Jul 16 (Print Publication: 2023).
Publication Year :
2023

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction caused by the fungus Aspergillus , and it is often treated with steroids or antifungal agents. However, long-term use of these medications can lead to infections and drug interactions. We present the case of a 71-year-old woman with ABPA who was diagnosed with hepatitis B and active hepatitis C, and sputum analysis revealed the presence of bacteria. Oral steroids were initially administered, but the patient was switched to mepolizumab because of numerous infectious complications. The early introduction of mepolizumab is effective in patients with ABPA complicated by infectious diseases.<br />Competing Interests: All authors of the manuscript declare that there are no conflicts of interest.<br /> (© 2023 Published by Elsevier Ltd.)

Details

Language :
English
ISSN :
2213-0071
Volume :
45
Database :
MEDLINE
Journal :
Respiratory medicine case reports
Publication Type :
Report
Accession number :
37560613
Full Text :
https://doi.org/10.1016/j.rmcr.2023.101890