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Prevalence of arsenic-induced skin lesions and associated factors in Ethiopia: Community-based study.

Authors :
Demissie S
Mekonen S
Awoke T
Teshome B
Mengistie B
Source :
Toxicology reports [Toxicol Rep] 2023 Jul 29; Vol. 11, pp. 153-161. Date of Electronic Publication: 2023 Jul 29 (Print Publication: 2023).
Publication Year :
2023

Abstract

The study aimed to assess the prevalence of arsenic-induced skin lesions and associated factors among the population in the Adami Tulu Jido Kombolcha district, Ethiopia. A community-based cross-sectional study design was employed among 403 participants from June 02-20, 2022. A two-stage cluster sampling method was conducted to select study subjects. A pretested structured and semi-structured interview questionnaire and observation using a WHO flow chart were used for data collection. Data analysis was performed using SPSS version 24 statistical software for Windows. A multivariable binary logistic regression model was applied to examine the relationship between predictor variables and an outcome variable. The degrees of association between outcomes and predictor variables were assessed using ORs and 95% CIs, and P-values < 0.05 were considered significant. The prevalence of arsenic-induced skin lesions (arsenicosis) in the study area was 2.2% [95% CI: 1.0-3.7]. The most common arsenic-induced manifestation was keratosis (55.6%), followed by hyperpigmentation (33.3%) and hyperkeratosis (11.1%). Consumption of well water, smoking cigarettes, and chewing khat were significantly associated with arsenic-induced skin lesions. Therefore, the findings of this study should trigger further research on arsenic exposure and health risks.<br />Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (© 2023 The Authors.)

Details

Language :
English
ISSN :
2214-7500
Volume :
11
Database :
MEDLINE
Journal :
Toxicology reports
Publication Type :
Academic Journal
Accession number :
37559672
Full Text :
https://doi.org/10.1016/j.toxrep.2023.07.007