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NHC-mediated photocatalytic deoxygenation of alcohols for the synthesis of internal alkynes via a Csp 3 -Csp coupling reaction.

Authors :
Ma X
Wang L
Meng X
Li W
Wang Q
Gu Y
Qiu L
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2023 Aug 23; Vol. 21 (33), pp. 6693-6696. Date of Electronic Publication: 2023 Aug 23.
Publication Year :
2023

Abstract

NHC-mediated deoxygenation of alcohols under photocatalytic conditions is described. The process provides various alkyl radicals, which can react with 1-bromoalkyne via Csp <superscript>3</superscript> -Csp coupling to afford internal alkynes in moderate to good yields. The method offers a new and convenient approach to synthesize internal alkynes.

Details

Language :
English
ISSN :
1477-0539
Volume :
21
Issue :
33
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
37548245
Full Text :
https://doi.org/10.1039/d3ob01066j