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Osteoporosis and Fracture Risk among Older US Asian Adults.
- Source :
-
Current osteoporosis reports [Curr Osteoporos Rep] 2023 Oct; Vol. 21 (5), pp. 592-608. Date of Electronic Publication: 2023 Aug 05. - Publication Year :
- 2023
-
Abstract
- Purpose of Review: This review summarizes the current knowledge regarding osteoporosis and fracture among older US Asian adults.<br />Recent Findings: Asian adults have lower (areal) bone density than non-Hispanic White adults and thus are more likely to be diagnosed and treated for osteoporosis, despite their lower risk of hip fracture. The latter may relate to favorable characteristics in hip geometry, volumetric bone density, and bone microarchitecture; lower risk of falls; and other clinical factors. The fracture risk calculator FRAX accounts for the lower risk of hip fracture among US Asian adults. However, data on major osteoporotic fracture risk remain limited. Fracture rates also vary by Asian subgroup, which may have implications for fracture risk assessment. Furthermore, among women receiving bisphosphonate drugs, Asian race is a risk factor for atypical femur fracture, an uncommon complication associated with treatment duration. Recent clinical trial efficacy data pertaining to lower bisphosphonate doses and longer dosing intervals may be relevant for Asian adults. More research is needed to inform osteoporosis care of US Asian adults, including risk-benefit considerations and the optimal duration of bisphosphonate treatment. Greater evidence-based guidance for primary fracture prevention among US Asian adults will ensure health equity in the prevention of osteoporotic fractures.<br /> (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Subjects :
- Adult
Female
Humans
Bone Density
Risk Factors
Risk Assessment
Diphosphonates therapeutic use
Osteoporosis drug therapy
Osteoporosis complications
Osteoporotic Fractures epidemiology
Osteoporotic Fractures prevention & control
Osteoporotic Fractures complications
Hip Fractures epidemiology
Hip Fractures prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1544-2241
- Volume :
- 21
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Current osteoporosis reports
- Publication Type :
- Academic Journal
- Accession number :
- 37542683
- Full Text :
- https://doi.org/10.1007/s11914-023-00805-7