Stereotactic radiotherapy for ultracentral lung tumours.

Authors :: Bourbonne V
Thureau S
Pradier O
Antoni D
Lucia F
Source :: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2023 Sep; Vol. 27 (6-7), pp. 659-665. Date of Electronic Publication: 2023 Jul 27.
Publication Year :: 2023
Abstract: Ultracentral (UC) lung lesions are generally defined by the presence of the tumour or the Planning Target Volume (PTV) abutting proximal bronchial tree (PBT) or the esophagus. Initial reports rose awareness regarding the potential toxicity of stereotactic body radiotherapy (SBRT) when delivered to UC lesions. Major concerns include necrosis, stenosis, and bleeding of the PBT. Technological improvements now enable the delivery of more accurate treatments, possibly redefining the historical "no-fly zone". In this review, studies focusing on the treatment of UC lesions with SBRT are presented. The narrow therapeutic window requires a multidisciplinary approach.<br /> (Copyright © 2023. Published by Elsevier Masson SAS.)

Subjects :: Bronchi
Esophagus
Constriction, Pathologic
Necrosis
Blood Loss, Surgical
Humans
Radiosurgery adverse effects
Lung Neoplasms pathology
Lung Neoplasms surgery
Margins of Excision

Language :: English
ISSN :: 1769-6658
Volume :: 27
Issue :: 6-7
Database :: MEDLINE
Journal :: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Publication Type :: Academic Journal
Accession number :: 37516640
Full Text :: https://doi.org/10.1016/j.canrad.2023.06.021