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A nomogram for predicting acute kidney injury following hepatectomy: A propensity score matching analysis.

Authors :
Kuang L
Lin W
Chen B
Wang D
Zeng Q
Source :
Journal of clinical anesthesia [J Clin Anesth] 2023 Nov; Vol. 90, pp. 111211. Date of Electronic Publication: 2023 Jul 20.
Publication Year :
2023

Abstract

Study Objective: The low central venous pressure (LCVP) technique is a key technique in hepatectomy, but its impact on acute kidney injury (AKI) is unclear. The purpose of this study was to explore risk factors (in particular LCVP time) for AKI following hepatectomy.<br />Design: A retrospective case-control study with propensity score matching.<br />Setting: Operating room.<br />Patients: A total of 1949 patients who underwent hepatectomy were studied.<br />Interventions: The patients were grouped with or without AKI within 7 days after surgery. Univariable and multivariable analyses were performed, including recognized intraoperative predictors. The final result is represented as a nomogram.<br />Measurements: Preoperative, intraoperative and postoperative data were collected. LCVP is monitored directly through a central venous catheter via the right internal jugular vein.<br />Main Results: AKI occurred in 148 patients (7.59%). Surgery time, minimum SBP, furosemide administration and norepinephrine were identified as independent risk factors. The area under the curve for the receiver operating characteristic curves was 0.726 (95% CI 0.668-0.783).<br />Conclusion: Intraoperative parameters can be used to predict the probability of postoperative AKI. Although AKI increases the length of stay, it may not increase in-hospital mortality. LCVP time was not confirmed to be a risk factor for AKI.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no competing interests.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1873-4529
Volume :
90
Database :
MEDLINE
Journal :
Journal of clinical anesthesia
Publication Type :
Academic Journal
Accession number :
37480714
Full Text :
https://doi.org/10.1016/j.jclinane.2023.111211