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Inability of chlorophenols to induce 6-thioguanine-resistant mutants in V79 Chinese hamster cells.
- Source :
-
Mutation research [Mutat Res] 1986 Aug-Sep; Vol. 171 (2-3), pp. 165-8. - Publication Year :
- 1986
-
Abstract
- The induction of mutation at the hypoxanthine-guanine phosphoribosyl transferase locus and cytotoxicities of 6 different chlorophenols (2,4- and 2,6-dichlorophenol, 2,4,5- and 2,4,6-trichlorophenol, 2,3,4,6-tetrachlorophenol and pentachlorophenol) were examined in V79 Chinese hamster cells without exogenous metabolic activation. The chlorophenols were cytotoxic to V79 cells, but failed to produce significant increases in the frequency of 6-thioguanine-resistant mutants.
Details
- Language :
- English
- ISSN :
- 0027-5107
- Volume :
- 171
- Issue :
- 2-3
- Database :
- MEDLINE
- Journal :
- Mutation research
- Publication Type :
- Academic Journal
- Accession number :
- 3748065
- Full Text :
- https://doi.org/10.1016/0165-1218(86)90050-9