Back to Search
Start Over
Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization.
- Source :
-
ACS sensors [ACS Sens] 2023 Jul 28; Vol. 8 (7), pp. 2415-2426. Date of Electronic Publication: 2023 Jul 18. - Publication Year :
- 2023
-
Abstract
- Antibodies are among the most relevant biomolecular targets for diagnostic and clinical applications. In this Perspective, we provide a critical overview of recent research efforts focused on the development and characterization of devices, switches, and reactions based on the use of synthetic antigen-conjugated DNA strands designed to be responsive to specific antibodies. These systems can find applications in sensing, drug-delivery, and antibody-antigen binding characterization. The examples described here demonstrate how the programmability and chemical versatility of synthetic nucleic acids can be used to create innovative analytical tools and target-responsive systems with promising potentials.
Details
- Language :
- English
- ISSN :
- 2379-3694
- Volume :
- 8
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- ACS sensors
- Publication Type :
- Academic Journal
- Accession number :
- 37463359
- Full Text :
- https://doi.org/10.1021/acssensors.3c00564