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Geriatric Depression Scale predicts mortality in elderly patients on chronic hemodialysis.

Authors :
Bossola M
Pepe G
Antocicco E
Illuminati C
Di Stasio E
Source :
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy [Ther Apher Dial] 2023 Dec; Vol. 27 (6), pp. 1088-1094. Date of Electronic Publication: 2023 Jul 12.
Publication Year :
2023

Abstract

Introduction: The aim of this study was to determine if the Geriatric Depression Scale (GDS) was predictor of mortality in elderly patients on chronic hemodialysis (HD).<br />Methods: A total of 140 HD patients ≥65 years were studied. Symptoms of depression were assessed through GDS and cognitive function through the Mini Mental State Examination (MMSE). GDS scores 0-9 are considered normal (Group 1); scores of 10-20 (Group 2) and 21-30 (Group 3) indicate mild and severe depression.<br />Results: Median GDS was 13 (11-15): 54 patients in Group 1, 49 in Group 2, and 37 in Group 3. After a follow-up of 58.85 ± 38.8 months, 94 patients died and 46 were alive. Kaplan-Meier survival was significantly lower in patients of Groups 2 and 3 than in Group 1 (log-rank χ <superscript>2</superscript> : 101.9; DF: 2; p < 0.0001). According to Cox regression analysis, mortality was associated with age and GDS, and inversely associated with MMSE and Kt/V.<br />Conclusion: GDS predicts mortality in elderly HD patients.<br /> (© 2023 International Society for Apheresis and Japanese Society for Apheresis.)

Details

Language :
English
ISSN :
1744-9987
Volume :
27
Issue :
6
Database :
MEDLINE
Journal :
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
Publication Type :
Academic Journal
Accession number :
37439003
Full Text :
https://doi.org/10.1111/1744-9987.14036